Efficient access to chiral dihydrobenzoxazinones via Rh-catalyzed hydrogenation

Rh/(S)-DTBM-SegPhos-catalyzed asymmetric hydrogenation of prochiral (Z)-2-(2-oxo-2H-benzo[b][1,4]oxazin-3(4H)-ylidene)acetate esters was successfully developed. A series of chiral dihydrobenzoxazinones were prepared through this efficient methodology with good to excellent results (up to >99% con...

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Detalles Bibliográficos
Autores principales: Chen, Ziyi, Yin, Xuguang, Dong, Xiu-Qin, Zhang, Xumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064260/
https://www.ncbi.nlm.nih.gov/pubmed/35514854
http://dx.doi.org/10.1039/c9ra02694k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064260/
https://www.ncbi.nlm.nih.gov/pubmed/35514854
http://dx.doi.org/10.1039/c9ra02694k

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