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Comprehensive quali-quantitative profiling of neutral and sialylated O-glycome by mass spectrometry based on oligosaccharide metabolic engineering and isotopic labeling

Mass spectrometry (MS) analysis combined with stable isotopic labeling is of great importance for quantitatively profiling abnormal sialylated O-glycans associated with disease development, but technically hindered by the poor releasing efficiency of O-glycans from glycoprotein or the labile nature...

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Detalles Bibliográficos
Autores principales: Nan, Lijing, Li, Jiao, Jin, Wanjun, Wei, Ming, Tang, Mengjun, Wang, Chengjian, Gong, Guiping, Huang, Linjuan, Zhang, Ying, Wang, Zhongfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064288/
https://www.ncbi.nlm.nih.gov/pubmed/35521403
http://dx.doi.org/10.1039/c9ra01114e