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Discovery and functional assessment of a novel adipocyte population driven by intracellular Wnt/β-catenin signaling in mammals

Wnt/β-catenin signaling has been well established as a potent inhibitor of adipogenesis. Here, we identified a population of adipocytes that exhibit persistent activity of Wnt/β-catenin signaling, as revealed by the Tcf/Lef-GFP reporter allele, in embryonic and adult mouse fat depots, named as Wnt(+...

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Detalles Bibliográficos
Autores principales: Liu, Zhi, Chen, Tian, Zhang, Sicheng, Yang, Tianfang, Gong, Yun, Deng, Hong-Wen, Bai, Ding, Tian, Weidong, Chen, YiPing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064292/
https://www.ncbi.nlm.nih.gov/pubmed/35503096
http://dx.doi.org/10.7554/eLife.77740