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Deletion of Calsyntenin-3, an atypical cadherin, suppresses inhibitory synapses but increases excitatory parallel-fiber synapses in cerebellum

Cadherins contribute to the organization of nearly all tissues, but the functions of several evolutionarily conserved cadherins, including those of calsyntenins, remain enigmatic. Puzzlingly, two distinct, non-overlapping functions for calsyntenins were proposed: As postsynaptic neurexin ligands in...

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Detalles Bibliográficos
Autores principales: Liu, Zhihui, Jiang, Man, Liakath-Ali, Kif, Sclip, Alessandra, Ko, Jaewon, Zhang, Roger Shen, Südhof, Thomas C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064300/
https://www.ncbi.nlm.nih.gov/pubmed/35420982
http://dx.doi.org/10.7554/eLife.70664