Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development

The embryonic extracellular matrix (ECM) undergoes transition to mature ECM as development progresses, yet few mechanisms ensuring ECM proteostasis during this period are known. Fibrillin microfibrils are macromolecular ECM complexes serving structural and regulatory roles. In mice, Fbn1 and Fbn2, e...

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Detalles Bibliográficos
Autores principales: Mead, Timothy J, Martin, Daniel R, Wang, Lauren W, Cain, Stuart A, Gulec, Cagri, Cahill, Elisabeth, Mauch, Joseph, Reinhardt, Dieter, Lo, Cecilia, Baldock, Clair, Apte, Suneel S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064305/
https://www.ncbi.nlm.nih.gov/pubmed/35503090
http://dx.doi.org/10.7554/eLife.71142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064305/
https://www.ncbi.nlm.nih.gov/pubmed/35503090
http://dx.doi.org/10.7554/eLife.71142

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