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Aerobic, metal-free synthesis of 6H-chromeno[4,3-b]quinolin-6-ones

A Friedländer-based method for transition-metal free, aerobic synthesis of chromene-fused quinolinones is reported. The coupling of 4-hydrocoumarins and 2-aminobenzyl alcohols proceeds in the presence of acetic acid solvent and oxygen oxidant, affording 6H-chromeno[4,3-b]quinolin-6-ones in good to e...

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Detalles Bibliográficos
Autores principales: Ton, Nhan N. H., Dang, Ha V., Phan, Nam T. S., Nguyen, Tung T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064357/
https://www.ncbi.nlm.nih.gov/pubmed/35521415
http://dx.doi.org/10.1039/c9ra02267h