Highly α-position regioselective ring-opening of epoxides catalyzed by halohydrin dehalogenase from Ilumatobacter coccineus: a biocatalytic approach to 2-azido-2-aryl-1-ols

Halohydrin dehalogenases are usually recognized as strict β-position regioselective enzymes in the nucleophile-mediated ring-opening of epoxides. Here we found the HheG from Ilumatobacter coccineus exhibited excellent α-position regioselectivity in the azide-mediated ring-opening of styrene oxide de...

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Detalles Bibliográficos
Autores principales: An, Miao, Liu, Wanyi, Zhou, Xiaoying, Ma, Ran, Wang, Huihui, Cui, Baodong, Han, Wenyong, Wan, Nanwei, Chen, Yongzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064361/
https://www.ncbi.nlm.nih.gov/pubmed/35516406
http://dx.doi.org/10.1039/c9ra03774h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064361/
https://www.ncbi.nlm.nih.gov/pubmed/35516406
http://dx.doi.org/10.1039/c9ra03774h

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