One-pot regioselective C–H activation iodination–cyanation of 2,4-diarylquinazolines using malononitrile as a cyano source

A one-pot cyanation of 2,4-arylquinazoline with NIS and malononitrile has been developed. The one-pot reaction includes two steps. The Rh-catalyzed selective C–H activation/iodization of 2,4-diarylquinazoline with NIS, and then Cu-catalyzed cyanation of the corresponding iodinated intermediate with...

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Detalles Bibliográficos
Autores principales: Yan, Ziqiao, Ouyang, Banlai, Mao, Xunchun, Gao, Wei, Deng, Zhihong, Peng, Yiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064619/
https://www.ncbi.nlm.nih.gov/pubmed/35515228
http://dx.doi.org/10.1039/c9ra02979f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064619/
https://www.ncbi.nlm.nih.gov/pubmed/35515228
http://dx.doi.org/10.1039/c9ra02979f

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