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Metastasis manners and the underlying mechanisms of ALK and ROS1 rearrangement lung cancer and current possible therapeutic strategies

The rearrangements of anaplastic lymphoma kinase (ALK) and the c-ros oncogene 1 (ROS1) have both been important driving factors in non-small-cell lung cancer (NSCLC). They have already been defined in 3–5% of NSCLC patients. ALK and ROS1 rearrangements are associated with unique clinical and patholo...

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Detalles Bibliográficos
Autores principales: Chang, Xing, Liu, Zi, Man, Shuai, Roys, Annie, Li, Zengqiang, Zuo, Daiying, Wu, Yingliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064669/
https://www.ncbi.nlm.nih.gov/pubmed/35520562
http://dx.doi.org/10.1039/c9ra02258a