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Molecular regulation of lung maturation in near-term fetal sheep by maternal daily vitamin C treatment in late gestation

BACKGROUND: In the fetus, the appropriate balance of prooxidants and antioxidants is essential to negate the detrimental effects of oxidative stress on lung maturation. Antioxidants improve respiratory function in postnatal life and adulthood. However, the outcomes and biological mechanisms of antio...

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Detalles Bibliográficos
Autores principales: McGillick, Erin V., Orgeig, Sandra, Allison, Beth J., Brain, Kirsty L., Niu, Youguo, Itani, Nozomi, Skeffington, Katie L., Kane, Andrew D., Herrera, Emilio A., Morrison, Janna L., Giussani, Dino A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064793/
https://www.ncbi.nlm.nih.gov/pubmed/33859366
http://dx.doi.org/10.1038/s41390-021-01489-4