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Anti-inflammatory effect of SGLT-2 inhibitors via uric acid and insulin

Sodium–glucose cotransporter 2 (SGLT-2) inhibitors (i) reduce cardiovascular and renal events in patients with and without type 2 diabetes (T2D). However, the underlying mechanisms are debated. Low-grade inflammation (LGI) is a key driver of vascular complications, suggested to be attenuated by SGLT...

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Detalles Bibliográficos
Autores principales: La Grotta, Rosalba, de Candia, Paola, Olivieri, Fabiola, Matacchione, Giulia, Giuliani, Angelica, Rippo, Maria Rita, Tagliabue, Elena, Mancino, Monica, Rispoli, Francesca, Ferroni, Sabina, Berra, Cesare Celeste, Ceriello, Antonio, Prattichizzo, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064844/
https://www.ncbi.nlm.nih.gov/pubmed/35503137
http://dx.doi.org/10.1007/s00018-022-04289-z