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6-Hydroxydopamine Induces Neurodegeneration in Terminally Differentiated SH-SY5Y Neuroblastoma Cells via Enrichment of the Nucleosomal Degradation Pathway: a Global Proteomics Approach

The SH-SY5Y human neuroblastoma cells have been used for decades as a cell-based model of dopaminergic neurons to explore the underlying science of cellular and molecular mechanisms of neurodegeneration in Parkinson’s disease (PD). However, data revealing the protein expression changes in 6-OHDA ind...

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Detalles Bibliográficos
Autores principales: Magalingam, Kasthuri Bai, Somanath, Sushela Devi, Ramdas, Premdass, Haleagrahara, Nagaraja, Radhakrishnan, Ammu Kutty
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064865/
https://www.ncbi.nlm.nih.gov/pubmed/35258800
http://dx.doi.org/10.1007/s12031-021-01962-z