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Exploiting LRRC15 as a Novel Therapeutic Target in Cancer

Abundant fibrotic stroma is a typical feature of most solid tumors, and stromal activation promotes oncogenesis, therapy resistance, and metastatic dissemination of cancer cells. Therefore, targeting the tumor stroma in combination with standard-of-care therapies has become a promising therapeutic s...

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Detalles Bibliográficos
Autores principales: Ray, Upasana, Pathoulas, Christopher L., Thirusangu, Prabhu, Purcell, James W., Kannan, Nagarajan, Shridhar, Viji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064950/
https://www.ncbi.nlm.nih.gov/pubmed/35260879
http://dx.doi.org/10.1158/0008-5472.CAN-21-3734