Remofuscin induces xenobiotic detoxification via a lysosome-to-nucleus signaling pathway to extend the Caenorhabditis elegans lifespan

Lipofuscin is a representative biomarker of aging that is generated naturally over time. Remofuscin (soraprazan) improves age-related eye diseases by removing lipofuscin from retinal pigment epithelium (RPE) cells. In this study, the effect of remofuscin on longevity in Caenorhabditis elegans and th...

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Detalles Bibliográficos
Autores principales: Oh, Miae, Yeom, Jiah, Schraermeyer, Ulrich, Julien-Schraermeyer, Sylvie, Lim, Young-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064964/
https://www.ncbi.nlm.nih.gov/pubmed/35504961
http://dx.doi.org/10.1038/s41598-022-11325-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064964/
https://www.ncbi.nlm.nih.gov/pubmed/35504961
http://dx.doi.org/10.1038/s41598-022-11325-2

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