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Remofuscin induces xenobiotic detoxification via a lysosome-to-nucleus signaling pathway to extend the Caenorhabditis elegans lifespan

Lipofuscin is a representative biomarker of aging that is generated naturally over time. Remofuscin (soraprazan) improves age-related eye diseases by removing lipofuscin from retinal pigment epithelium (RPE) cells. In this study, the effect of remofuscin on longevity in Caenorhabditis elegans and th...

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Detalles Bibliográficos
Autores principales:	Oh, Miae, Yeom, Jiah, Schraermeyer, Ulrich, Julien-Schraermeyer, Sylvie, Lim, Young-Hee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064964/ https://www.ncbi.nlm.nih.gov/pubmed/35504961 http://dx.doi.org/10.1038/s41598-022-11325-2

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