TH17 cells promote CNS inflammation by sensing danger signals via Mincle

The C-type lectin receptor Mincle is known for its important role in innate immune cells in recognizing pathogen and damage associated molecular patterns. Here we report a T cell–intrinsic role for Mincle in the pathogenesis of experimental autoimmune encephalomyelitis (EAE). Genomic deletion of Min...

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Detalles Bibliográficos
Autores principales: Zhang, Quanri, Liu, Weiwei, Wang, Han, Zhou, Hao, Bulek, Katarzyna, Chen, Xing, Zhang, Cun-Jin, Zhao, Junjie, Zhang, Renliang, Liu, Caini, Kang, Zizhen, Bermel, Robert A., Dubyak, George, Abbott, Derek W., Xiao, Tsan Sam, Nagy, Laura E., Li, Xiaoxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064974/
https://www.ncbi.nlm.nih.gov/pubmed/35504893
http://dx.doi.org/10.1038/s41467-022-30174-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064974/
https://www.ncbi.nlm.nih.gov/pubmed/35504893
http://dx.doi.org/10.1038/s41467-022-30174-1

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