Validated liquid chromatography tandem mass spectrometry for simultaneous quantification of foretinib and lapatinib, and application to metabolic stability investigation

Foretinib (GSK1363089, FTB) is a multikinase inhibitor that inhibits multiple receptor tyrosine kinases, including vascular endothelial growth factor receptor-2 and mesenchymal–epithelial transition factor, with the potential for solid tumor treatment. Lapatinib (LPB) is a significant promising drug...

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Detalles Bibliográficos
Autores principales: Alanazi, Mohammed M., Alkahtani, Hamad M., Almehizia, Abdulrahman A., Attwa, Mohamed W., Bakheit, Ahmed H., Darwish, Hany W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064977/
https://www.ncbi.nlm.nih.gov/pubmed/35519400
http://dx.doi.org/10.1039/c9ra03251g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064977/
https://www.ncbi.nlm.nih.gov/pubmed/35519400
http://dx.doi.org/10.1039/c9ra03251g

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