Cargando…
Validated liquid chromatography tandem mass spectrometry for simultaneous quantification of foretinib and lapatinib, and application to metabolic stability investigation
Foretinib (GSK1363089, FTB) is a multikinase inhibitor that inhibits multiple receptor tyrosine kinases, including vascular endothelial growth factor receptor-2 and mesenchymal–epithelial transition factor, with the potential for solid tumor treatment. Lapatinib (LPB) is a significant promising drug...
Autores principales: | Alanazi, Mohammed M., Alkahtani, Hamad M., Almehizia, Abdulrahman A., Attwa, Mohamed W., Bakheit, Ahmed H., Darwish, Hany W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9064977/ https://www.ncbi.nlm.nih.gov/pubmed/35519400 http://dx.doi.org/10.1039/c9ra03251g |
Ejemplares similares
-
Metabolic Stability Assessment of Larotrectinib Using Liquid Chromatography Tandem Mass Spectrometry
por: Attwa, Mohamed W, et al.
Publicado: (2020) -
Liquid chromatography tandem mass spectrometry method for the quantification of vandetanib in human plasma and rat liver microsomes matrices: metabolic stability investigation
por: Amer, Sawsan M., et al.
Publicado: (2017) -
Characterization of in vivo metabolites in rat urine following an oral dose of masitinib by liquid chromatography tandem mass spectrometry
por: Kadi, Adnan A., et al.
Publicado: (2018) -
Reactive intermediates in naquotinib metabolism identified by liquid chromatography-tandem mass spectrometry: phase I metabolic profiling
por: Attwa, Mohamed W., et al.
Publicado: (2019) -
Simultaneous Quantification of Multiple Urinary Naphthalene Metabolites by Liquid Chromatography Tandem Mass Spectrometry
por: Ayala, Daniel C., et al.
Publicado: (2015)