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Structural basis for the synthesis of the core 1 structure by C1GalT1

C1GalT1 is an essential inverting glycosyltransferase responsible for synthesizing the core 1 structure, a common precursor for mucin-type O-glycans found in many glycoproteins. To date, the structure of C1GalT1 and the details of substrate recognition and catalysis remain unknown. Through biophysic...

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Detalles Bibliográficos
Autores principales: González-Ramírez, Andrés Manuel, Grosso, Ana Sofia, Yang, Zhang, Compañón, Ismael, Coelho, Helena, Narimatsu, Yoshiki, Clausen, Henrik, Marcelo, Filipa, Corzana, Francisco, Hurtado-Guerrero, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065035/
https://www.ncbi.nlm.nih.gov/pubmed/35504880
http://dx.doi.org/10.1038/s41467-022-29833-0