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Pseudotyped Bat Coronavirus RaTG13 is efficiently neutralised by convalescent sera from SARS-CoV-2 infected patients

RaTG13 is a close relative of SARS-CoV-2, the virus responsible for the COVID-19 pandemic, sharing 96% sequence similarity at the genome-wide level. The spike receptor binding domain (RBD) of RaTG13 contains a number of amino acid substitutions when compared to SARS-CoV-2, likely impacting affinity...

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Detalles Bibliográficos
Autores principales: Cantoni, Diego, Mayora-Neto, Martin, Thakur, Nazia, Elrefaey, Ahmed M. E., Newman, Joseph, Vishwanath, Sneha, Nadesalingam, Angalee, Chan, Andrew, Smith, Peter, Castillo-Olivares, Javier, Baxendale, Helen, Charleston, Bryan, Heeney, Jonathan, Bailey, Dalan, Temperton, Nigel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065041/
https://www.ncbi.nlm.nih.gov/pubmed/35505237
http://dx.doi.org/10.1038/s42003-022-03325-9