Improved engraftment and therapeutic efficacy by human genome-edited hematopoietic stem cells with Busulfan-based myeloablation

Autologous hematopoietic stem cell transplantation using genome-edited cells can become a definitive therapy for hematological and non-hematological disorders with neurological involvement. Proof-of-concept studies using human genome-edited hematopoietic stem cells have been hindered by the low effi...

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Detalles Bibliográficos
Autores principales: Poletto, Edina, Colella, Pasqualina, Pimentel Vera, Luisa N., Khan, Shaukat, Tomatsu, Shunji, Baldo, Guilherme, Gomez-Ospina, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065050/
https://www.ncbi.nlm.nih.gov/pubmed/35573043
http://dx.doi.org/10.1016/j.omtm.2022.04.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065050/
https://www.ncbi.nlm.nih.gov/pubmed/35573043
http://dx.doi.org/10.1016/j.omtm.2022.04.009

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