MSD-based assays facilitate a rapid and quantitative serostatus profiling for the presence of anti-AAV antibodies

Adeno-associated virus (AAV) vector applications are often limited by capsid-directed humoral immune responses, mainly through neutralizing antibodies (NAbs), which are present throughout the human population due to natural AAV infections. Currently, antibody levels are often quantified via ELISA-ba...

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Detalles Bibliográficos
Autores principales: Haar, Janina, Blazevic, Dragica, Strobel, Benjamin, Kreuz, Sebastian, Michelfelder, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065051/
https://www.ncbi.nlm.nih.gov/pubmed/35573045
http://dx.doi.org/10.1016/j.omtm.2022.04.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065051/
https://www.ncbi.nlm.nih.gov/pubmed/35573045
http://dx.doi.org/10.1016/j.omtm.2022.04.008

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