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MSD-based assays facilitate a rapid and quantitative serostatus profiling for the presence of anti-AAV antibodies
Adeno-associated virus (AAV) vector applications are often limited by capsid-directed humoral immune responses, mainly through neutralizing antibodies (NAbs), which are present throughout the human population due to natural AAV infections. Currently, antibody levels are often quantified via ELISA-ba...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065051/ https://www.ncbi.nlm.nih.gov/pubmed/35573045 http://dx.doi.org/10.1016/j.omtm.2022.04.008 |