Alternative splicing modulation by G-quadruplexes

Alternative splicing is central to metazoan gene regulation, but the regulatory mechanisms are incompletely understood. Here, we show that G-quadruplex (G4) motifs are enriched ~3-fold near splice junctions. The importance of G4s in RNA is emphasised by a higher enrichment for the non-template stran...

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Detalles Bibliográficos
Autores principales: Georgakopoulos-Soares, Ilias, Parada, Guillermo E., Wong, Hei Yuen, Medhi, Ragini, Furlan, Giulia, Munita, Roberto, Miska, Eric A., Kwok, Chun Kit, Hemberg, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065059/
https://www.ncbi.nlm.nih.gov/pubmed/35504902
http://dx.doi.org/10.1038/s41467-022-30071-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065059/
https://www.ncbi.nlm.nih.gov/pubmed/35504902
http://dx.doi.org/10.1038/s41467-022-30071-7

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