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Rapid access to polycyclic N-heteroarenes from unactivated, simple azines via a base-promoted Minisci-type annulation

Conventional synthetic methods to yield polycyclic heteroarenes have largely relied on metal-mediated arylation reactions requiring pre-functionalised substrates. However, the functionalisation of unactivated azines has been restricted because of their intrinsic low reactivity. Herein, we report a t...

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Detalles Bibliográficos
Autores principales: Lee, Jae Bin, Kim, Gun Ha, Jeon, Ji Hwan, Jeong, Seo Yeong, Lee, Soochan, Park, Jaehyun, Lee, Doyoung, Kwon, Youngkook, Seo, Jeong Kon, Chun, Joong-Hyun, Kang, Seok Ju, Choe, Wonyoung, Rohde, Jan-Uwe, Hong, Sung You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065069/
https://www.ncbi.nlm.nih.gov/pubmed/35504905
http://dx.doi.org/10.1038/s41467-022-30086-0