MrgprF acts as a tumor suppressor in cutaneous melanoma by restraining PI3K/Akt signaling

The incidence of cutaneous melanoma (CM) has been increasing annually worldwide. In this study, we identify that MrgprF, a MAS related GPR family member, is decreased in cutaneous melanoma tissues and cell lines due to hypermethylation of its promoter region, and show that patients with CM expressin...

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Detalles Bibliográficos
Autores principales: Shen, Qiushuo, Han, Yanfei, Wu, Kai, He, Yaomei, Jiang, Xiulin, Liu, Peishen, Xia, Cuifeng, Xiong, Qiuxia, Liu, Rui, Chen, Qianming, Zhang, Yong, Zhao, Song, Yang, Cuiping, Chen, Yongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065076/
https://www.ncbi.nlm.nih.gov/pubmed/35504869
http://dx.doi.org/10.1038/s41392-022-00945-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065076/
https://www.ncbi.nlm.nih.gov/pubmed/35504869
http://dx.doi.org/10.1038/s41392-022-00945-9

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