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Generalizing predictions to unseen sequencing profiles via deep generative models

Predictive models trained on sequencing profiles often fail to achieve expected performance when externally validated on unseen profiles. While many factors such as batch effects, small data sets, and technical errors contribute to the gap between source and unseen data distributions, it is a challe...

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Detalles Bibliográficos
Autores principales: Oh, Min, Zhang, Liqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065080/
https://www.ncbi.nlm.nih.gov/pubmed/35504956
http://dx.doi.org/10.1038/s41598-022-11363-w