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Functional identification of microRNA-centered complexes in C. elegans

microRNAs (miRNAs) are crucial for normal development and physiology. To identify factors that might coordinate with miRNAs to regulate gene expression, we used 2′O-methylated oligonucleotides to precipitate Caenorhabditis elegans let-7, miR-58, and miR-2 miRNAs and the associated proteins. A total...

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Detalles Bibliográficos
Autores principales: Hebbar, Shilpa, Panzade, Ganesh, Vashisht, Ajay A., Wohlschlegel, James A., Veksler-Lublinsky, Isana, Zinovyeva, Anna Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065084/
https://www.ncbi.nlm.nih.gov/pubmed/35504914
http://dx.doi.org/10.1038/s41598-022-10771-2