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A comparison of strategies for generating artificial replicates in RNA-seq experiments

Due to the overall high costs, technical replicates are usually omitted in RNA-seq experiments, but several methods exist to generate them artificially. Bootstrapping reads from FASTQ-files has recently been used in the context of other NGS analyses and can be used to generate artificial technical r...

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Detalles Bibliográficos
Autores principales: Saremi, Babak, Gusmag, Frederic, Distl, Ottmar, Schaarschmidt, Frank, Metzger, Julia, Becker, Stefanie, Jung, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065086/
https://www.ncbi.nlm.nih.gov/pubmed/35505053
http://dx.doi.org/10.1038/s41598-022-11302-9