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A human pancreatic ECM hydrogel optimized for 3-D modeling of the islet microenvironment

Extracellular matrix (ECM) plays a multitude of roles, including supporting cells through structural and biochemical interactions. ECM is damaged in the process of isolating human islets for clinical transplantation and basic research. A platform in which islets can be cultured in contact with natur...

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Detalles Bibliográficos
Autores principales: Tremmel, Daniel M., Sackett, Sara Dutton, Feeney, Austin K., Mitchell, Samantha A., Schaid, Michael D., Polyak, Erzsebet, Chlebeck, Peter J., Gupta, Sakar, Kimple, Michelle E., Fernandez, Luis A., Odorico, Jon S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065104/
https://www.ncbi.nlm.nih.gov/pubmed/35504932
http://dx.doi.org/10.1038/s41598-022-11085-z