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High-throughput analysis of single human cells reveals the complex nature of DNA replication timing control
DNA replication initiates from replication origins firing throughout S phase. Debate remains about whether origins are a fixed set of loci, or a loose agglomeration of potential sites used stochastically in individual cells, and about how consistent their firing time is. We develop an approach to pr...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065153/ https://www.ncbi.nlm.nih.gov/pubmed/35504890 http://dx.doi.org/10.1038/s41467-022-30212-y |