Mapping transgene insertion sites reveals the α-Cre transgene expression in both developing retina and olfactory neurons

The Tg(Pax6-cre,GFP)(2Pgr) (α-Cre) mouse is a commonly used Cre line thought to be retinal-specific. Using targeted locus amplification (TLA), we mapped the insertion site of the transgene, and defined primers useful to deduce zygosity. Further analyses revealed four tandem copies of the transgene....

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Detalles Bibliográficos
Autores principales: Fan, Yimeng, Chen, Wenyue, Wei, Ran, Qiang, Wei, Pearson, Joel D., Yu, Tao, Bremner, Rod, Chen, Danian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065156/
https://www.ncbi.nlm.nih.gov/pubmed/35505181
http://dx.doi.org/10.1038/s42003-022-03379-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065156/
https://www.ncbi.nlm.nih.gov/pubmed/35505181
http://dx.doi.org/10.1038/s42003-022-03379-9

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