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Sodium tanshinone IIA silate increases melanin synthesis by activating the MAPK and PKA pathways and protects melanocytes from H(2)O(2)-induced oxidative stress

Vitiligo is an intriguing depigmentation disorder that affects about 0.5–2% of the world population. In the past decade, first-line treatments of vitiligo have involved the use of calcineurin inhibitors and corticosteroids. Sodium tanshinone IIA sulfonate (STS) has been widely applied in the treatme...

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Detalles Bibliográficos
Autores principales: Zhong, Hui, An, Xiaohong, Li, Yu, Cai, Minxuan, Ahmad, Owais, Shang, Jing, Zhou, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065168/
https://www.ncbi.nlm.nih.gov/pubmed/35516905
http://dx.doi.org/10.1039/c8ra09786k