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Shh and Olig2 sequentially regulate oligodendrocyte differentiation from hiPSCs for the treatment of ischemic stroke

Rationale: Demyelination is a major component of white matter injury, characterized by oligodendrocyte (OL) death and myelin sheath loss, which result in memory loss and cognitive impairment in the context of ischemic stroke. Accumulating evidence has shown that OLs can be generated by the direct ac...

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Detalles Bibliográficos
Autores principales: Xu, Jian, Zhao, Jingxin, Wang, Rui, Zhang, Yidi, Shen, Lan, Xiao, Qian, Xie, Yuan, Jiang, Jinjun, Nie, Yichu, Deng, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065175/
https://www.ncbi.nlm.nih.gov/pubmed/35547747
http://dx.doi.org/10.7150/thno.69217