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Polymer chimera of stapled oncolytic peptide coupled with anti-PD-L1 peptide boosts immunotherapy of colorectal cancer

Rationale: Scarce tumor mutation burden and neoantigens create tremendous obstacles for an effective immunotherapy of colorectal cancer (CRC). Oncolytic peptides rise as a promising therapeutic approach that boosts tumor-specific immune responses by inducing antigenic substances. However, the clinic...

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Detalles Bibliográficos
Autores principales: Lu, Lu, Zhang, He, Zhou, Yudong, Lin, Jiayi, Gao, Weidong, Yang, Ting, Jin, Jinmei, Zhang, Lijun, Nagle, Dale G., Zhang, Weidong, Wu, Ye, Chen, Hongzhuan, Luan, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065177/
https://www.ncbi.nlm.nih.gov/pubmed/35547769
http://dx.doi.org/10.7150/thno.71129