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Optimized mobilization of MHC class I- and II- restricted immunity by dendritic cell vaccine potentiates cancer therapy

Background: The participation of major histocompatibility complex (MHC) in antigen presentation shapes both the breadth and magnitude of specific T cell response. Dendritic cells (DCs) activated with nucleic acid or protein that encodes/incorporates multiple antigenic epitopes elicit MHC class I- an...

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Detalles Bibliográficos
Autores principales: Shi, Yingying, Liu, Yu, Huang, Jiaxin, Luo, Zhenyu, Guo, Xuemeng, Jiang, Mengshi, Li, Xiang, Lu, Yichao, Liu, Xu, Shan, Xinyu, Luo, Lihua, You, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065178/
https://www.ncbi.nlm.nih.gov/pubmed/35547749
http://dx.doi.org/10.7150/thno.71760