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SCD1/FADS2 fatty acid desaturases equipoise lipid metabolic activity and redox-driven ferroptosis in ascites-derived ovarian cancer cells

Rationale: Malignant ascites in peritoneal metastases is a lipid-enriched microenvironment and is frequently involved in the poor prognosis of epithelial ovarian cancer (EOC). However, the detailed mechanisms underlying ovarian cancer (OvCa) cells dictating their lipid metabolic activities in promot...

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Detalles Bibliográficos
Autores principales: Xuan, Yang, Wang, Huogang, Yung, Mingo MH, Chen, Fushun, Chan, Wai-Sun, Chan, Yau-Sang, Tsui, Stephen KW, Ngan, Hextan YS, Chan, Karen KL, Chan, David W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065188/
https://www.ncbi.nlm.nih.gov/pubmed/35547771
http://dx.doi.org/10.7150/thno.70194