Mitochondria-targeted supramolecular coordination container encapsulated with exogenous itaconate for synergistic therapy of joint inflammation

Rationale: Inflammatory macrophages and osteoclasts (OCs) play critical roles in joint inflammation, which feature the excessive production of reactive oxygen species (ROS), resulting in synovial inflammation and bone erosion. Scavenging ROS, especially by modulating mitochondrial metabolic activity...

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Detalles Bibliográficos
Autores principales: Chen, Xuzhuo, Li, Chang, Cao, Xiankun, Jia, Xinlin, Chen, Xinwei, Wang, Zhenqiang, Xu, Weifeng, Dai, Fengrong, Zhang, Shanyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065189/
https://www.ncbi.nlm.nih.gov/pubmed/35547753
http://dx.doi.org/10.7150/thno.70623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065189/
https://www.ncbi.nlm.nih.gov/pubmed/35547753
http://dx.doi.org/10.7150/thno.70623

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