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Acidic microenvironment triggered in situ assembly of activatable three-arm aptamer nanoclaw for contrast-enhanced imaging and tumor growth inhibition in vivo

Rationale: Static assembled multivalent DNA nanotheranostics system have encountered some bottleneck problems in cancer imaging and therapy, such as poor penetration and high immunogenicity. Herein, we proposed an acidic tumor microenvironment triggered assembly of activatable multivalent nanodevice...

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Detalles Bibliográficos
Autores principales: Huang, Jin, Wu, Yuchen, He, Hui, Ma, Wenjie, Liu, Jianbo, Cheng, Hong, Sun, Huanhuan, He, Xiaoxiao, Wang, Kemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065194/
https://www.ncbi.nlm.nih.gov/pubmed/35547767
http://dx.doi.org/10.7150/thno.72028