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Neuronal STAT3/HIF-1α/PTRF axis-mediated bioenergetic disturbance exacerbates cerebral ischemia-reperfusion injury via PLA2G4A

Ischemic stroke is an acute and severe neurological disease with high mortality and disability rates worldwide. Polymerase I and transcript release factor (PTRF) plays a pivotal role in regulating cellular senescence, glucose intolerance, lipid metabolism, and mitochondrial bioenergetics, but its me...

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Detalles Bibliográficos
Autores principales: Jin, Weili, Zhao, Jixing, Yang, Eryan, Wang, Yunfei, Wang, Qixue, Wu, Ye, Tong, Fei, Tan, Yanli, Zhou, Junhu, Kang, Chunsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065197/
https://www.ncbi.nlm.nih.gov/pubmed/35547748
http://dx.doi.org/10.7150/thno.71029