Multi-scale integrative analyses identify THBS2(+) cancer-associated fibroblasts as a key orchestrator promoting aggressiveness in early-stage lung adenocarcinoma

Rationale: Subsets of patients with early-stage lung adenocarcinoma (LUAD) have a poor post-surgical course after curative surgery. However, biomarkers stratifying this high-risk subset and molecular underpinnings underlying the aggressive phenotype remain unclear. Methods: We integrated bulk and si...

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Detalles Bibliográficos
Autores principales: Yang, Haitang, Sun, Beibei, Fan, Liwen, Ma, Wenyan, Xu, Ke, Hall, Sean R. R., Wang, Zhexin, Schmid, Ralph A., Peng, Ren-Wang, Marti, Thomas M., Gao, Wen, Xu, Jianlin, Yang, Weiwei, Yao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065207/
https://www.ncbi.nlm.nih.gov/pubmed/35547750
http://dx.doi.org/10.7150/thno.69590

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065207/
https://www.ncbi.nlm.nih.gov/pubmed/35547750
http://dx.doi.org/10.7150/thno.69590

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