The Apoptotic Resistance of BRCA1-Deficient Ovarian Cancer Cells is Mediated by cAMP

Breast cancer type 1 susceptibility protein (BRCA1) is essential for homologous recombination repair of DNA double-strand breaks. Loss of BRCA1 is lethal to embryos due to extreme genomic instability and the activation of p53-dependent apoptosis. However, the apoptosis is resisted in BRCA1-deficient...

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Detalles Bibliográficos
Autores principales: Yue, Wei, Ma, Jihong, Xiao, Yinan, Wang, Pan, Gu, Xiaoyang, Xie, Bingteng, Li, Mo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065249/
https://www.ncbi.nlm.nih.gov/pubmed/35517499
http://dx.doi.org/10.3389/fcell.2022.889656

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065249/
https://www.ncbi.nlm.nih.gov/pubmed/35517499
http://dx.doi.org/10.3389/fcell.2022.889656

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