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The Risk of Ventricular Dysrhythmia or Sudden Death in Patients Receiving Serotonin Reuptake Inhibitors With Methadone: A Population-Based Study

Background: Methadone is associated with ventricular dysrhythmias and sudden death. Serotonin reuptake inhibitors (SRIs) may increase the risk of these events either by inhibiting metabolism of methadone’s proarrhythmic (S)-enantiomer, additive QT interval prolongation, or both. We sought to determi...

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Detalles Bibliográficos
Autores principales: Antoniou, Tony, McCormack, Daniel, Tadrous, Mina, Juurlink, David N., Gomes, Tara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065276/
https://www.ncbi.nlm.nih.gov/pubmed/35517813
http://dx.doi.org/10.3389/fphar.2022.861953