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The Unusual Cosubstrate Specificity of NQO2: Conservation Throughout the Amniotes and Implications for Cellular Function

Human Quinone Reductase 2 (NQO2) is a pharmacological target and has appeared in numerous screening efforts as an off-target interactor with kinase-targeted drugs. However the cellular functions of NQO2 are not known. To gain insight into the potential cellular functions of NQO2, we have carried out...

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Detalles Bibliográficos
Autores principales: Islam, Faiza, Leung, Kevin K., Walker, Matthew D., Al Massri, Shahed, Shilton, Brian H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065289/
https://www.ncbi.nlm.nih.gov/pubmed/35517822
http://dx.doi.org/10.3389/fphar.2022.838500