Phthalimide Analogs Enhance Genotoxicity of Cyclophosphamide and Inhibit Its Associated Hypoxia

Cyclophosphamide (CP) is a mutagen that is used in cancer chemotherapy, due to its genotoxicity and as an immunosuppressive agent. Thalidomide (TH) is another cancer chemotherapeutic drug. In this study, the cytogenotoxicity and hypoxia modulatory activities of two phthalimide analogs of TH have bee...

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Detalles Bibliográficos
Autores principales: Gamal-Eldeen, Amira M., Agwa, Hussein S., Zahran, Magdy A.-H., Raafat, Bassem M., El-Daly, Sherien M., Banjer, Hamsa J., Almehmadi, Mazen M., Alharthi, Afaf, Hawsawi, Nahed M., Althobaiti, Fayez, Abo-Zeid, Mona A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065290/
https://www.ncbi.nlm.nih.gov/pubmed/35518717
http://dx.doi.org/10.3389/fchem.2022.890675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065290/
https://www.ncbi.nlm.nih.gov/pubmed/35518717
http://dx.doi.org/10.3389/fchem.2022.890675

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