Computational elucidation of the binding mechanisms of curcumin analogues as bacterial RecA inhibitors

Antimicrobial resistance (AMR) presents as a serious threat to global public health, which urgently demands action to develop alternative antimicrobial strategies with minimized selective pressure. The bacterial SOS response regulator RecA has emerged as a promising target in the exploration of new...

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Detalles Bibliográficos
Autores principales: Zhou, Zi-Yuan, Yuan, Jing, Pan, Qing, Mo, Xiao-Mei, Xie, Yong-Li, Yin, Feng, Li, Zigang, Wong, Nai-Kei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065326/
https://www.ncbi.nlm.nih.gov/pubmed/35519399
http://dx.doi.org/10.1039/c9ra00064j