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Prediction of DNA-Binding Protein–Drug-Binding Sites Using Residue Interaction Networks and Sequence Feature

Identification of protein–ligand binding sites plays a critical role in drug discovery. However, there is still a lack of targeted drug prediction for DNA-binding proteins. This study aims at the binding sites of DNA-binding proteins and drugs, by mining the residue interaction network features, whi...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Zhang, Yu, Liu, Dong, Zhang, HongJun, Wang, XianFang, Zhou, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065339/
https://www.ncbi.nlm.nih.gov/pubmed/35519609
http://dx.doi.org/10.3389/fbioe.2022.822392