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Evaluation of Potential Herb-Drug Interactions Between Shengmai Injection and Losartan Potassium in Rat and In Vitro

Aim: The present study aimed to explore the potential herb-drug interactions (HDI) between Shengmai injection (SMI) and losartan potassium (LOS) based on the expression profiles of cytochromes P450 (CYP450) and drug transporters in rat and in vitro. Methods: Different concentrations of SMI were used...

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Detalles Bibliográficos
Autores principales: Niu, Zhenchao, Qiang, Tingting, Lin, Wenyong, Li, Yiping, Wang, Keyan, Wang, Dan, Wang, Xiaolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065348/
https://www.ncbi.nlm.nih.gov/pubmed/35517807
http://dx.doi.org/10.3389/fphar.2022.878526