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Evaluation of Potential Herb-Drug Interactions Between Shengmai Injection and Losartan Potassium in Rat and In Vitro
Aim: The present study aimed to explore the potential herb-drug interactions (HDI) between Shengmai injection (SMI) and losartan potassium (LOS) based on the expression profiles of cytochromes P450 (CYP450) and drug transporters in rat and in vitro. Methods: Different concentrations of SMI were used...
Autores principales: | Niu, Zhenchao, Qiang, Tingting, Lin, Wenyong, Li, Yiping, Wang, Keyan, Wang, Dan, Wang, Xiaolong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065348/ https://www.ncbi.nlm.nih.gov/pubmed/35517807 http://dx.doi.org/10.3389/fphar.2022.878526 |
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