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Notoamide-type alkaloid induced apoptosis and autophagy via a P38/JNK signaling pathway in hepatocellular carcinoma cells

Bioassay-guided fractionation of a coral-associated fungus Aspergillus ochraceus LZDX-32-15 resulted in the isolation of eleven notoamide-type alkaloids, including four new congeners, namely notoamides W-Z (1–4). The structures of the new alkaloids were determined by extensive analyses of spectrosco...

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Detalles Bibliográficos
Autores principales: Hu, Likun, Zhang, Ting, Liu, Dong, Guan, Guiwen, Huang, Jian, Proksch, Peter, Chen, Xiangmei, Lin, Wenhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065365/
https://www.ncbi.nlm.nih.gov/pubmed/35519412
http://dx.doi.org/10.1039/c9ra03640g